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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
26.97
Human Site:
Y404
Identified Species:
37.08
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
Y404
E
N
P
E
M
L
K
Y
Q
R
R
Q
Q
Q
Q
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
Y404
E
N
P
E
M
L
K
Y
Q
R
R
Q
Q
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
Q525
N
P
E
M
L
K
Y
Q
R
R
Q
Q
Q
Q
Q
Dog
Lupus familis
XP_543550
1017
111618
Y404
E
N
P
E
M
L
K
Y
Q
R
R
Q
Q
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
Y404
E
N
P
E
M
L
K
Y
Q
R
R
Q
Q
Q
Q
Rat
Rattus norvegicus
NP_001129232
1015
111665
Y404
E
N
P
E
M
L
K
Y
Q
R
R
Q
Q
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
Y404
E
N
P
E
M
L
K
Y
Q
Q
R
Q
Q
Q
Q
Frog
Xenopus laevis
Q8QFR2
1013
112021
F404
E
N
P
E
M
L
K
F
Q
Q
R
Q
Q
L
Q
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
Y404
E
N
P
E
M
L
K
Y
Q
Q
E
R
Q
G
N
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
K404
I
E
N
P
E
M
L
K
Y
Q
Q
E
R
R
N
Fruit Fly
Dros. melanogaster
O17468
1047
113397
Q401
P
Q
R
L
L
L
P
Q
G
D
K
P
T
K
F
Honey Bee
Apis mellifera
XP_001122939
838
91355
E250
G
P
T
A
Q
I
I
E
R
D
G
W
T
Q
D
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
G347
L
L
A
C
S
Q
D
G
T
V
K
V
I
H
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
S376
K
E
L
G
H
R
L
S
D
S
E
M
D
E
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
K404
L
L
E
T
A
S
T
K
Q
A
G
S
K
R
A
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
A252
Q
H
I
A
V
P
N
A
T
N
G
P
V
S
S
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
G402
G
G
S
R
K
G
M
G
T
A
E
D
V
D
G
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
33.3
100
N.A.
100
100
N.A.
N.A.
93.3
80
66.6
0
6.6
6.6
0
N.A.
P-Site Similarity:
100
100
53.3
100
N.A.
100
100
N.A.
N.A.
100
93.3
80
40
26.6
20
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
6.6
0
0
P-Site Similarity:
N.A.
13.3
N.A.
20
20
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
12
6
0
0
6
0
12
0
0
0
0
6
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
0
6
12
0
6
6
6
6
% D
% Glu:
48
12
12
48
6
0
0
6
0
0
18
6
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% F
% Gly:
12
6
0
6
0
6
0
12
6
0
18
0
0
6
6
% G
% His:
0
6
0
0
6
0
0
0
0
0
0
0
0
6
0
% H
% Ile:
6
0
6
0
0
6
6
0
0
0
0
0
6
0
0
% I
% Lys:
6
0
0
0
6
6
48
12
0
0
12
0
6
6
0
% K
% Leu:
12
12
6
6
12
53
12
0
0
0
0
0
0
6
6
% L
% Met:
0
0
0
6
48
6
6
0
0
0
0
6
0
0
0
% M
% Asn:
6
48
6
0
0
0
6
0
0
6
0
0
0
0
12
% N
% Pro:
6
12
48
6
0
6
6
0
0
0
0
12
0
0
0
% P
% Gln:
6
6
0
0
6
6
0
12
53
24
12
48
53
48
48
% Q
% Arg:
0
0
6
6
0
6
0
0
12
36
42
6
6
12
0
% R
% Ser:
0
0
6
0
6
6
0
6
0
6
0
6
0
6
6
% S
% Thr:
0
0
6
6
0
0
6
0
18
0
0
0
12
0
0
% T
% Val:
0
0
0
0
6
0
0
0
0
6
0
6
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
6
% W
% Tyr:
0
0
0
0
0
0
6
42
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _